Endocrine Abstracts

Introduction: The GEP NEN (gastroentero-pancreatic neuroendocrine neoplasms) are 70% of all neuroendocrine tumors, but are rare in general population – constituting only 2% of the gastrointestinal tract neoplasms. Carcinoid stands for 50% of GEP NEN, most often located in the appendix and/or ileum. Although the detection of NEN is rising, their prevalence is still likely underestimated. The clinical presentation is not characteristic at the early stages of the disease, it...

Introduction: Mitotane-o’p-DDD belongs to insecticides (DDT pesticide contamination), it is the only drug registered by the FDA in treatment in adrenocortical carcinoma (ACC). Treatment effect is controled by mitotane concentration in the blood.Aim: The aim of the study is to evaluate the effectiveness of mitotane treatment in patients with adrenocortical cancer.Material and methods: We retrospectively reviewed data on ACC pat...